姜玉钦

姜玉钦


姜玉钦,河南镇平人。博士,教授,药物化学、生物与医药硕士生导师,现代工学院副院长。E-mail: yuqinjiang2018@163.com

河南省科技创新杰出青年

河南省教育厅学术技术带头人

河南省手性醇类药物工程技术研究中心主任

化学制药及生物医用材料河南省工程实验室主任

河南省药学会药物化学专业委员会副主任委员

九三学社新乡市第八届监督委员会委员

新乡市第九批优秀专家

河南省知识产权专家库专家


  

教育经历:
1998.09-2002.07 
3499cc拉斯维加斯化学与环境科学学院,精细化工专业,工学学士,指导教师 娄向东教授;
2002.09-2005.07 
3499cc拉斯维加斯化学与环境科学学院,应用化学专业,工学硕士,导师 李伟教授;
2005.09-2008.12 
南开大学高分子化学研究所,高分子化学与物理专业,理学博士,导师 陈永胜教授。

工作经历:

2009.01-2010.12  郑州大学化学系,分析化学博士后,合作导师 屈凌波教授;

2011.01-2015.03  3499cc拉斯维加斯化学与环境科学学院,讲师,硕士生导师;

2015.04-2021.03  3499cc拉斯维加斯化学化工学院,副教授;其中2020年11月起任教务处副处长;

2021.04-2024.01  3499cc拉斯维加斯化学化工学院,教授。

2024.01-至今       3499cc拉斯维加斯化学化工学院,教授,任3499cc拉斯维加斯现代工学院副院长。           

讲授课程:

《药物分析》《化学制药工艺学》《药物分析及制药检测常用技术》《药物分析实验》《药物分析综合实验》

研究领域与兴趣:

1、抗肿瘤创新药物

2、药物合成工艺

3、有机反应方法学

4、高分子生物医用材料

近年来主持(参与)的主要科研教学项目:
1
、河南省科技创新杰出青年人才支持计划:高品质曲克芦丁原料药合成关键技术及产业化研究,2017.01-2018.1230万元。

2、河南省产学研项目:维脑路通原料药生产新工艺及产业化研究,2015.01-2016.1225万元。

3、横向项目:曲克芦丁化学合成新工艺,2014.05-2016.1250万元。

4、横向项目:阿托伐他汀钙原料药新工艺研究,2017.11-2021.12100万元。

5、横向项目:抗肿瘤新药的研究与开发,2019.01-2024.01100万元。

6、横向项目:抗过敏药物工艺开发及DMF文件制作,2019.10-2025.02150万元。

7、河南省高等教育教学改革研究与实践重点项目:生物与医药硕士创新及联合培养基地建设研究与实践,2019-2021,3万元

8、河南省专业学位研究生精品教学案例项目:制药工艺与技术,2021-20223万元

9、2021年度河南省高等教育教学改革研究与实践重大项2022-2024,10万元,第四参与人。

10、3499cc拉斯维加斯优秀科技创新团队:药物研究与开发创新团队,2022-202430万元。

11、河南省高等学校重点科研项目计划基础研究专项:2023-202530万元。

12、2024年度河南省高等教育教学改革研究与实践重大项2024-2026,10万元,第三参与人。  

近年来发表论文:

36、Weiwei Zhang, Yuxi Li, Yixing Wei, Yuqin Jiang*, Zhiguo Hu*, Qingcong Wei*, Antibacterial carboxymethyl chitosan hydrogel loaded with antioxidant cascade enzymatic system for immunoregulating the diabetic wound microenvironment, International Journal of Biological Macromolecules, 2024, 282, 137539.

35、Jinjin Zhao, Jie Zhao, Fei Lin, Lili Xu, Zhigang Chen, Yuqin Jiang*, and Guoan Zhao*A quinoline-2-thione derivative as a novel chemotherapy drug candidate display anti-tumor activity In vitro and In vivo, BMC Cancer, 2024, 24, 1272.

34、Chunhua Ma*, Qing Guo, Hui Meng, Shengnan Yan, Qingjie Ding, Yuqin Jiang*, and Bing Yu*, Photoredox-catalyzed carbamoyl radical-initiated dearomative spirocyclization to access spiro-cyclohexadiene oxindoles, Organic Letters, 2024, 26, 8503-8508.

33、Ting Li, Zhichao Yang, Zhiqing Wang, Zhenzhen Peng, Guojiang Mao,Yuqin Jiang*, Chun-Yan Li*, A tumor-targeting dual-modal imaging probe for nitroreductase in vivo, Bioorganic Chemistry, 2024, 149, 107531.

32、Yinghui Huang, Linhui Shen, Chunhua Ma*, Yuqin Jiang,*and Bing Yu*, Functionalization of 1,3-butadiene derivatives under photo/electrocatalysis. European Journal of Organic Chemistry, 2024, 27(28), e202400403 (1 of 16). 

31Guiqing Xu, Jiayuan Lv, Qingjie Ding, Chunhua Ma*, Yuqin Jiang,* and Bing Yu*, Direct C–H alkylation of benzothiadiazoles via organic photoredox catalysis. The Journal of Organic Chemistry, 2024, 89 (4), 2777-2781.

30、Chunhua Ma*, Mengjiao Liu, Siyu Ouyang, Zhenwei Cui, Jingjing Bi, Yuqin Jiang,* and Zhiguo Zhang*, Metal-free construction of diverse 1,2,4-triazolo[1,5-a]pyridines on water. Chinese Chemical Letters, 2025, 36, 109755.

29、Chunhua Ma, Xiaofeng Li, Xiya Chen, Xing He, Shuting Zhang,* Yuqin Jiang,* and Bing Yu*, Photocatalytic umpolung strategy for the synthesis of α-amino phosphine oxides and deuterated derivatives. Organic Letters, 2023, 25, 8016-8021.

28、Danfeng Wang, Jin Wang, Chunhua Ma*, Yuqin Jiang,* and Bing Yu*, C-3 functionalization of 2-aryl-2h-indazoles under photo/electrocatalysis. Chinese Journal of Organic Chemistry, 2022, 42, 4024-4036.

27、Chunhua Ma, Yu Tian, Junyan Wang, Xing He, Yuqin Jiang,and  Bing Yu,* Visible-Light-driven transition-metal-free site-selective access to isonicotinamides. Organic Letters, 2022, 24, 8265-8270.

26、Chunhua Ma, Hui Meng, Jing Li, Xianguang Yang, Yuqin Jiang,* and  Bing Yu,* Photocatalytic transition-metal-free direct 3-acetalation of quinoxaline-2(1H)-ones. Chinese Journal of Chemistry, 2022, 40, 2655-2662.

25、Jin Wang, Qingyuan Song, Xing He, Chunhua Ma,* Yuqin Jiang,* and Jing Fan,* Visible light-promoted, photocatalyst-free decarboxylative alkylation of 2H-indazoles via electron donor-acceptor complex activation. New Journal of Chemistry, 2022, 46, 16436-16439.

24、Chunhua Ma, Hui Meng, Xing He, Yuqin Jiang* and Bing Yu*, Visible-light-promoted transition-metal-free construction of 3-perfluoroalkylated thioflavones, Frontiers in Chemistry, 2022, 10:953978.

23、Chunhua Ma, Lu Zhao, Xing He, Yuqin Jiang*, and Bing Yu*, Visible-light-induced direct 3-ethoxycarbonylmethylation of 2-qaryl-2H-indazoles in water, Organic Chemistry Frontiers, 2022, 9, 1445-1450.

22、Chunhua Ma, Yu Ji, Jie Zhao, Xing He, Shuting Zhang,* Yuqin Jiang,* and Bing Yu*. Transition-metal-free three-component acetalation-pyridylation of alkenes via photoredox catalysis.  Chinese Journal of Catalysis, 2022, 43, 571-583.

21、Chunhua Ma*, Qingyun Li, Minghao Zhao, Goujie Fan, Jie Zhao, Dandan Zhang, Shouning Yang, Shuting Zhang, Dingding Gao, Longfei Mao, Liang Zhu, Wei Li, Guiqing Xu,* Yuqin Jiang,* and Qingjie Ding*. Discovery of 1-amino-1h-imidazole-5-carboxamide derivatives as highly selective, covalent Bruton’s Tyrosine Kinase (BTK) inhibitors.  Journal of Medicinal Chemistry, 202164(21), 16242-16270. 

20、Dandan Zhang#, Guiqing Xu#, Jie Zhao#, Yue Wang, Xiaofang Wu, Xing He, Wei Li, Shuting Zhang, Shouning Yang, Chunhua Ma*, Yuqin Jiang*, Qingjie Ding*. Structure-activity relationship investigation for imidazopyrazole-3-carboxamide derivatives as novel selective inhibitors of Bruton's tyrosine kinase. European Journal of Medicinal Chemistry, 2021, 225, 113724(1-23).

19、Chunhua Ma, Ming Chen, Zhiwen Feng, Yan Zhang, Jin Wang, Yuqin Jiang,and Bing Yu*. Functionalization of imidazo[1,2-a]pyridines via radical reactions. New Journal of Chemistry, 2021, 45, 9302-9314.

18、Chunhua MaZhiwen Feng, Jing Li, Dandan Zhang, Wei Li, Yuqin Jiang* and Bing Yu*. Photocatalytic transition-metal-free direct 3-alkylation of 2-aryl-2h-indazoles in dimethyl carbonate, Organic Chemistry Frontiers, 2021, 8, 3286-3291.

17Yusang Xia, Ling Yan, Guojiang Mao, Wenli Jiang, Wenxin Wang, Yongfei Li, Yuqin Jiang*, and Chunyan Li*. A novel HPQ-based fluorescent probe for the visualization of carbon monoxide in zebrafish, Sensors and Actuators B: Chemical, 2021, 340, 129920 (1-7).

16、Yuqin Jiang, Pengfei Li, Jie Zhao, Bingxian Liu*, and Xingwei Li*. Iodonium ylides as carbene precursors in Rh(III)-catalyzed C-H activation, Organic Letters, 2020, 22(19), 7475-7479.

15、Yuqin Jiang, Lu Jiang, Yuanyuan Pang, Dan Kai, Xiaoshan Fan*, and Zibiao Li*. Surface migration of fluorinated-siloxane copolymer with unusual liquid crystal behavior for highly efficient oil/water separation, ACS Applied Polymer Materials, 2020, 2, 3612-3620.

14、Yuqin Jiang, Jing Li, Zhiwen Feng, Guiqing Xu, Xin Shi, Qingjie Ding, Wei Li, Chunhua Ma* and Bing Yu*. Ethylene glycol: a green solvent for visible light-promoted aerobic transition metal-free cascade sulfonation/cyclization reaction, Advanced Synthesis & Catalysis, 2020 362(13), 2609-2614.

13Yuqin Jiang, Pengfei Li, Juanjuan Wang, Jie Zhao, Yang Li, Yawen Zhang, Junbiao Chang*, Bingxian Liu* and Xingwei Li*. Rh(III)-catalyzed coupling of acrylic acids and ynenones via olefinic C-H activation and Michael addition, Organic Letters, 2020, 22(2), 438-442.

12Yuqin Jiang, Yanyan Li, Tingting Yang, Xin Shi*, Huajun Suo, Weiwei Zhang* Guiqing Xu and Wei Li*. Design, synthesis, and antilung adenocarcinoma activity research of novel paeonol Schiff base derivatives containing a 1,2,3-triazole moiety, Journal of the Chinese Chemical Society, 2020, 67(1), 165-171.

11TingtingYang, Xin Shi, Libing Guo, Shaohua Gu, Weiwei Zhang, Guiqing Xu, Wei Li* and Yuqin Jiang*. Design, synthesis, and antitumor activity of novel paeonol derivatives containing the 1,4-benzoxazinone and 1,2,3-triazole moieties, Journal of Chemical Research, 2019, 43(7-8), 241-247.

10Yuqin Jiang, Kai Wu, Qian Zhang,* Keqing Li, Yanyan Li, Pengyang Xin, Weiwei Zhang and Haiming Guo*. A dual-responsive hyperbranched supramolecular polymer constructed by cooperative host-guest recognition and hydrogen-bond interactions, Chemical Communications, 2018, 54, 13821-13824.

9Yuqin Jiang, Kai Wu, Liming Fan, Jinglin Zhao, Yuqing Yang, Weiwei Zhang* and Guiqing Xu*. Cu(OAc)2H2O/NH2OH·HCl/CH3COONa: A facile and efficient catalyst system for copper-catalyzed azide-alkyne click reactions in water, Journal of the Chinese Chemical Society, 2018, 65, 505-510.

8Yuqin Jiang, Shuhong Jia, Xiyong Li, Yamin Sun, Wei Li, Weiwei Zhang, Guiqing Xu. An efficient NaHSO3-promoted protocol for chemoselective synthesis of 2-substituted benzimidazoles in water, Chemical Papers, 2018, 72, 1265-1276.

7Yuqin Jiang, Huajun Suo, Yaru Zhao, Xiyong Li, Yamin Sun, Xingfeng Li, Wenpei Dong, Wei Li, Weiwei Zhang* and Guiqing Xu. DBU-promoted Cu(OAc)2·H2O-catalysed coupling reactions of aryl iodides and sodium azide, Journal of Chemical Research, 2018, 42, 247-250.

6Yuqin Jiang, Kai Wu, Xuxia Tan, Dandan Zhang, Wenpei Dong, Wei Li, Guiqing Xu and Weiwei Zhang*. [bmim]PF6/KOH: a recyclable catalytic system for an azide-arylacetaldehyde [3+2] cycloaddition, Journal of Chemical Research, 2017, 41, 631-635.

5Yuqin Jiang, Shuhong Jia, Xiyong Li, Yamin Sun, Wei Li, Weiwei Zhang* and Guiqing Xu*. Design, synthesis, and antifungal evaluation of novel benzoxazole derivatives containing a 1,2,3-triazole moiety, Journal of the Chinese Chemical Society, 2017, 64, 1197-1202.

4Yuqin Jiang,* Xingfeng Li, Yaru Zhao, Shuhong Jia, Mingrui Li, Zhiqi Zhao, Ruili Zhang, Wei Li and Weiwei Zhang*. An efficient CuI/DBU-catalyzed one-pot protocol for synthesis of 1,4-disubstituted 1,2,3-triazoles, RSC Advances, 2016, 6, 110102-110107.

3Yuqin Jiang,* Xing He, Weiwei Zhang, Xingfeng Li, Niu Guo, Yaru Zhao, Guiqing Xu* and Wei Li. Metallic copper wire: a simple, clear and reusable catalyst for the CuAAC reaction in supercritical carbon dioxide, RSC Advances, 2015, 5, 73340-73345.

2Weiwei Zhang, Baoqi Ren, Yuqin Jiang* and Zhiguo Hu*. Carboxymethylpullulan promoted Cu2O-catalyzed Huisgen-click reaction, RSC Advances, 2015, 5, 12043-12047.

1Weiwei Zhang, Xing He, Baoqi Ren, Yuqin Jiang* and Zhiguo Hu*. Cu(OAc)2·H2O-an efficient catalyst for Huisgen-click reaction in supercritical carbon dioxide, Tetrahedron Letters, 2015, 56, 2472-2475.

授权专利:

14、姜玉钦 等,一种2-苯基-2H-吲唑-3-甲酰胺类化合物的光催化制备方法,202210993884.X,2024年。

13、姜玉钦 等,一种高含量曲克芦丁的制备方法ZL201810308308.02023年。

12、姜玉钦 等,一种表达COVID-19抗原的表达载体及基因工程乳酸菌口服疫苗的构建方法,ZL202010677960.72023年。

11、姜玉钦 等,一种2-(2-苯基-2H-吲唑-3-基)乙酸酯类化合物的水相光催化制备方法,ZL202111024843.12023年。

10、姜玉钦 等,WO2022012550 A1, 2022年。

9、姜玉钦 等,WO2021110142 A1, 2021年。

8、姜玉钦 等,WO2020228637 A1, 2020年。

7姜玉钦 等,一种阿托伐他汀钙中间体ATS-9的纯化方法,ZL 201811169986.X2020年。

6、姜玉钦 等,一种高纯度福多司坦的制备方法,ZL 201810560947.62020年。

5、姜玉钦 等,一种高含量曲克芦丁的制备方法,ZL 201710119984.92020年。

4、姜玉钦 等,一种奈拉西坦的制备方法,ZL 201410766319.52017年。

3、姜玉钦 等,一种采用自吸式搅拌高压釜制备曲克芦丁的方法,ZL 201410766698.82017年。

2、姜玉钦 等,具有抑菌活性的烯唑醇-1,2,3-三氮唑类化合物及其制备方法,ZL 201410184618.82016年。

1、姜玉钦 等,一种沙坦联苯的制备方法,ZL 201310383875.X2015年。

科技奖励:

5、阿托伐他汀钙原料药技术创新及在制剂生产中的产业化应用,河南省科技进步奖二等奖,第二完成人,2024。

4、阿托伐他汀钙原料药技术创新及在制剂生产中的产业化应用,科学技术成果评价,第二完成人,2024。

3、曲克芦丁关键技术创新及产业化应用,河南省科技进步奖二等奖,第十完成人,2023年。

2、曲克芦丁合成关键技术创新及产业化,河南省教育厅科技成果奖一等奖,第一完成人,2020年。

1、阿托伐他汀钙关键技术研究与产业化,河南省科学技术进步奖叁等奖,第四完成人,2014年。

个人荣誉:

    国普通高等学校本科教育教学评估专家、九三学社河南省第九届委员会高层次人才工作委员会委员、新乡市新医药产业链重点企业战略联盟专家委员会委员、学术桥评审专家库成员、河南省化学会常务理事、新乡市九三学社“社内监督工作先进个人”“参政议政工作先进个人”;新乡市第九批优秀专家;河南省抗击新冠肺炎疫情先进个人;河南省科技创新杰出青年;河南省高层次人才C类;河南省优秀硕士学位论文指导教师;河南省高校科技管理工作先进工作者;河南省高等学校优秀共产党员;新乡市九三学社抗击新冠肺炎疫情先进个人暨社会服务先进个人;中国“互联网+”大学生创新创业大赛全国铜奖指导教师;3499cc拉斯维加斯首届“卢锦梭师德楷模奖教金”获得者、“急难险重先进个人”“青年五四奖章”“优秀教师”“三育人先进个人”“研究生优秀指导教师”等。



Individual Profile: Yuqin Jiang, PhD, associate professor, School of Chemistry and Chemical Engineering, Henan Normal University. E-mail: yuqinjiang2018@163.com.

Education:
1998.09-2002.06 School of Chemistry and Environmental Sciences, Henan Normal University, Bachelor of Engineering;
2002.09-2005.06 S
chool of Chemistry and Environmental Sciences, Henan Normal University, Master of Engineering;
2005.09-2008.12
Institute of Polymer Chemistry, Nankai University, Doctor of Science.

Professional Experience:

2011.01, School of Chemistry and Environmental Sciences, Henan Normal University;

2015.04, School of Chemistry and Chemical Engineering, Henan Normal University, associate professor;

2009.01-2011.01, Department Chemistry, Zhengzhou University, analytical chemistry postgraduate.

Research Interests:

1Anti-tumor Drug Design and Synthesis

2Pharmaceutical Technology

3、Methodology of Organic Synthesis

4、Functional Polymer Materials

Research Support:
1
Innovative Talents Program of Henan Province (No. 174100510025): Research on the key technology and industrialization of high-purity bulk drug troxerutin, Role: PI, 2017.1-2018.12, 300K.

2Research on the new technology and industrialization of drug Venoruton, Role: PI, 2015.1-2016.12,250K.

3New synthetic process for troxerutin, Role: PI, 2014.5-2016.12, 500K.

4New synthetic process for atorvastatin calcium, Role: PI, 2017.11-2021.12, 1000K.

5Anti-tumor drug design and synthesis, Role: PI, 2019.01-2022.01, 1000K.

6New synthetic process for antiallergic agent, Role: PI, 2019.10-2021.02, 1500K.

7 、Postgraduate Education Reform Project of Henan Province, Role: PI, 2019-2021, 30K.

Representative Publications:

36、Weiwei Zhang, Yuxi Li, Yixing Wei, Yuqin Jiang*, Zhiguo Hu*, Qingcong Wei*, Antibacterial carboxymethyl chitosan hydrogel loaded with antioxidant cascade enzymatic system for immunoregulating the diabetic wound microenvironment, International Journal of Biological Macromolecules, 2024, 282, 137539.

35、Jinjin Zhao, Jie Zhao, Fei Lin, Lili Xu, Zhigang Chen, Yuqin Jiang*, and Guoan Zhao*A quinoline-2-thione derivative as a novel chemotherapy drug candidate display anti-tumor activity In vitro and In vivoBMC Cancer, 2024, 24, 1272.

34、Chunhua Ma*, Qing Guo, Hui Meng, Shengnan Yan, Qingjie Ding, Yuqin Jiang*, and Bing Yu*, Photoredox-catalyzed carbamoyl radical-initiated dearomative spirocyclization to access spiro-cyclohexadiene oxindoles, Organic Letters2024, 26, 8503-8508.

33、Ting Li, Zhichao Yang, Zhiqing Wang, Zhenzhen Peng, Guojiang Mao,Yuqin Jiang*, Chun-Yan Li*tumor-targeting dual-modal imaging probe for nitroreductase in vivoBioorganic Chemistry, 2024, 149, 107531.

32、Yinghui Huang, Linhui Shen, Chunhua Ma*, Yuqin Jiang,*and Bing Yu*, Functionalization of 1,3-butadiene derivatives under photo/electrocatalysis. European Journal of Organic Chemistry, 2024, 27(28), e202400403 (1 of 16). 

31Guiqing Xu, Jiayuan Lv, Qingjie Ding, Chunhua Ma*, Yuqin Jiang,* and Bing Yu*, Direct C–H alkylation of benzothiadiazoles via organic photoredox catalysis. The Journal of Organic Chemistry, 2024, 89 (4), 2777-2781.

30、Chunhua Ma*, Mengjiao Liu, Siyu Ouyang, Zhenwei Cui, Jingjing Bi, Yuqin Jiang*, Zhiguo Zhang*, Metal-free construction of diverse 1,2,4-triazolo[1,5-a]pyridines on water. Chinese Chemical Letters, 2024,  36, 109755.

29、Chunhua Ma, Xiaofeng Li, Xiya Chen, Xing He, Shuting Zhang,* Yuqin Jiang,* and Bing Yu*, Photocatalytic umpolung strategy for the synthesis of α-amino phosphine oxides and deuterated derivatives. Organic Letters, 202325, 8016-8021.

28、Danfeng Wang, Jin Wang, Chunhua Ma*, Yuqin Jiang,* and Bing Yu*, C-3 functionalization of 2-aryl-2h-indazoles under photo/electrocatalysis. Chinese Journal of Organic Chemistry2022, 42,  4024-4036.

27、Chunhua Ma, Yu Tian, Junyan Wang, Xing He, Yuqin Jiang,and  Bing Yu,* Visible-Light-driven transition-metal-free site-selective access to isonicotinamides. Organic Letters, 2022, 24, 8265-8270.

26、Chunhua Ma, Hui Meng, Jing Li, Xianguang Yang, Yuqin Jiang,and  Bing Yu,* Photocatalytic transition-metal-free direct 3-acetalation of quinoxaline-2(1H)-ones. Chinese Journal of Chemistry2022, 40, 2655-2662.

25、Jin Wang, Qingyuan Song, Xing He, Chunhua Ma,* Yuqin Jiang,* Jing Fan,* Visible light-promoted, photocatalyst-free decarboxylative alkylation of 2H-indazoles via electron donor-acceptor complex activation. New Journal of Chemistry2022, 46, 16436-16439.

24、Chunhua Ma, Hui Meng, Xing He, Yuqin Jiang* and Bing Yu*, Visible-light-promoted transition-metal-free construction of 3-perfluoroalkylated thioflavones, Frontiers in Chemistry, 2022,  10:2022.953978.

23、Chunhua Ma, Lu Zhao, Xing He, Yuqin Jiang*, Bing Yu*, Visible-light-induced direct 3-ethoxycarbonylmethylation of 2-qaryl-2H-indazoles in water, Organic Chemistry Frontiers2022, DOI: 10.1039/D1QO01870A.

22、Chunhua Ma, Yu Ji, Jie Zhao, Xing He, Shuting Zhang,* Yuqin Jiang,* and Bing Yu*. Transition-metal-free three-component acetalation-pyridylation of alkenes via photoredox catalysis.  Chinese Journal of Catalysis, 2022, 43, 571-583.

21、Chunhua Ma*, Qingyun Li, Minghao Zhao, Goujie Fan, Jie Zhao, Dandan Zhang, Shouning Yang, Shuting Zhang, Dingding Gao, Longfei Mao, Liang Zhu, Wei Li, Guiqing Xu,* Yuqin Jiang,* and Qingjie Ding*. Discovery of 1-amino-1h-imidazole-5-carboxamide derivatives as highly selective, covalent Bruton’s Tyrosine Kinase (BTK) inhibitors.  Journal of Medicinal Chemistry, 202164(21), 16242-16270. 

20、Dandan Zhang#, Guiqing Xu#, Jie Zhao#, Yue Wang, Xiaofang Wu, Xing He, Wei Li, Shuting Zhang, Shouning Yang, Chunhua Ma*, Yuqin Jiang,* and Qingjie Ding*. Structure-activity relationship investigation for imidazopyrazole-3-carboxamide derivatives as novel selective inhibitors of Bruton's tyrosine kinase. European Journal of Medicinal Chemistry, 2021, 225, 113724(1-23).

19、Chunhua Ma, Ming Chen, Zhiwen Feng, Yan Zhang, Jin Wang, Yuqin Jiang,* and Bing Yu*. Functionalization of imidazo[1,2-a]pyridines via radical reactions. New Journal of Chemistry, 2021, 45, 9302-9314.

18、Chunhua MaZhiwen Feng, Jing Li, Dandan Zhang, Wei Li, Yuqin Jiang,* and Bing Yu*. Photocatalytic transition-metal-free direct 3-alkylation of 2-aryl-2h-indazoles in dimethyl carbonate, Organic Chemistry Frontiers2021,  2021, 8, 3286-3291.

17Yusang Xia, Ling Yan, Guojiang Mao, Wenli Jiang, Wenxin Wang, Yongfei Li, and Yuqin Jiang*, and Chunyan Li*. A novel HPQ-based fluorescent probe for the visualization of carbon monoxide in zebrafish, Sensors and Actuators B: Chemical2021, 340, 129920 (1-7).

16、Yuqin Jiang, Pengfei Li, Jie Zhao, Bingxian Liu,* and Xingwei Li*. Iodonium ylides as carbene precursors in Rh(III)-catalyzed C-H Activation, Organic Letters, 2020, 22(19), 7475-7479.

15、Yuqin Jiang, Lu Jiang, Yuanyuan Pang, Dan Kai, Xiaoshan Fan*, and Zibiao Li*. Surface migration of fluorinated-siloxane copolymer with unusual liquid crystal behavior for highly efficient oil/water separation, ACS Applied Polymer Materials, 2020, 2, 3612-3620.

14、Yuqin JiangJing Li, Zhiwen Feng, Guiqing Xu, Xin Shi, Qingjie Ding, Wei Li, Chunhua Ma* and Bing Yu*. Ethylene glycol: a green solvent for visible light-promoted aerobic transition metal-free cascade sulfonation/cyclization reaction, Advanced Synthesis & Catalysis, 2020, 362(13), 2609-2614.

13Yuqin Jiang, Pengfei Li, Juanjuan Wang, Jie Zhao, Yang Li, Yawen Zhang, Junbiao Chang*, Bingxian Liu* and Xingwei Li*. Rh(III)-catalyzed coupling of acrylic acids and ynenones via olefinic C-H activation and Michael addition, Organic Letters, 2020, 22(2), 438-442.

12Yuqin Jiang, Yanyan Li, Tingting Yang, Xin Shi*, Huajun Suo, Weiwei Zhang* Guiqing Xu and Wei Li*. Design, synthesis, and antilung adenocarcinoma activity research of novel paeonol Schiff base derivatives containing a 1,2,3-triazole moiety, Journal of the Chinese Chemical Society, 2020, 67(1), 165-171.

11TingtingYang, Xin Shi, Libing Guo, Shaohua Gu, Weiwei Zhang, Guiqing Xu, Wei Li* and Yuqin Jiang*. Design, synthesis, and antitumor activity of novel paeonol derivatives containing the 1,4-benzoxazinone and 1,2,3-triazole moieties, Journal of Chemical Research, 2019, 43(7-8), 241-247.

10Yuqin Jiang, Kai Wu, Qian Zhang,* Keqing Li, Yanyan Li, Pengyang Xin, Weiwei Zhang and Haiming Guo*. A dual-responsive hyperbranched supramolecular polymer constructed by cooperative host-guest recognition and hydrogen-bond interactions, Chemical Communications, 2018, 54, 13821-13824.

9Yuqin Jiang, Kai Wu, Liming Fan, Jinglin Zhao, Yuqing Yang, Weiwei Zhang* and Guiqing Xu*. Cu(OAc)2H2O/NH2OH·HCl/CH3COONa: A facile and efficient catalyst system for copper-catalyzed azide-alkyne click reactions in water, Journal of the Chinese Chemical Society, 2018, 65, 505-510.

8Yuqin Jiang, Shuhong Jia, Xiyong Li, Yamin Sun, Wei Li, Weiwei Zhang, Guiqing Xu. An efficient NaHSO3-promoted protocol for chemoselective synthesis of 2-substituted benzimidazoles in water, Chemical Papers, 2018, 72, 1265-1276.

7Yuqin Jiang, Huajun Suo, Yaru Zhao, Xiyong Li, Yamin Sun, Xingfeng Li, Wenpei Dong, Wei Li, Weiwei Zhang* and Guiqing Xu. DBU-promoted Cu(OAc)2·H2O-catalysed coupling reactions of aryl iodides and sodium azide, Journal of Chemical Research, 2018, 42, 247-250.

6Yuqin Jiang, Kai Wu, Xuxia Tan, Dandan Zhang, Wenpei Dong, Wei Li, Guiqing Xu and Weiwei Zhang*. [bmim]PF6/KOH: a recyclable catalytic system for an azide-arylacetaldehyde [3+2] cycloaddition, Journal of Chemical Research, 2017, 41, 631-635.

5Yuqin Jiang, Shuhong Jia, Xiyong Li, Yamin Sun, Wei Li, Weiwei Zhang* and Guiqing Xu*. Design, synthesis, and antifungal evaluation of novel benzoxazole derivatives containing a 1,2,3-triazole moiety, Journal of the Chinese Chemical Society, 2017, 64, 1197-1202.

4Yuqin Jiang,* Xingfeng Li, Yaru Zhao, Shuhong Jia, Mingrui Li, Zhiqi Zhao, Ruili Zhang, Wei Li and Weiwei Zhang*. An efficient CuI/DBU-catalyzed one-pot protocol for synthesis of 1,4-disubstituted 1,2,3-triazoles, RSC Advances, 2016, 6, 110102-110107.

3Yuqin Jiang,* Xing He, Weiwei Zhang, Xingfeng Li, Niu Guo, Yaru Zhao, Guiqing Xu* and Wei Li. Metallic copper wire: a simple, clear and reusable catalyst for the CuAAC reaction in supercritical carbon dioxide, RSC Advances, 2015, 5, 73340-73345.

2Weiwei Zhang, Baoqi Ren, Yuqin Jiang* and Zhiguo Hu*. Carboxymethylpullulan promoted Cu2O-catalyzed Huisgen-click reaction, RSC Advances, 2015, 5, 12043-12047.

1Weiwei Zhang, Xing He, Baoqi Ren, Yuqin Jiang* and Zhiguo Hu*. Cu(OAc)2·H2O-an efficient catalyst for Huisgen-click reaction in supercritical carbon dioxide, Tetrahedron Letters, 2015, 56, 2472-2475.

 



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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