详细介绍

朱功名,男,博士,副教授,综合办公室主任,药理学支部书记

联系方式:zhugm1201@163.com






教育经历:

20079-20116月  3499cc拉斯维加斯  生命科学学院

20119-20176月  兰州大学    生命科学学院  硕博连读  博士  导师:王锐院士


工作经历:

20177-20187月  中山大学     特聘副研究员  药物化学研究

20189-20235月  3499cc拉斯维加斯  化学化工学院

20235-至今     3499cc拉斯维加斯  抗病毒性传染病创新药物全国重点实验室


研究领域与兴趣:

1.核苷药物设计合成及筛选

2.多肽药物的定向合成及关键技术的开发

3.活性多肽后修饰及其化学生物学研究

4.核酸及多肽化学生物学研究


近年来主持的主要科研项目:

1.国家自然科学青年基金,2019-2021年,主持,资助金额:27.5万元。

2.广东省自然科学基金,2018-2021年,主持,资助金额:10万元。

3.3499cc拉斯维加斯博士启动经费,2019-2021年,主持,资助金额:8万。

4.参与完成国家自然科学青年基金2项,其中一项被评为优秀;

5.参与国家重点研发计划2项,重点项目1项,面上项目3项。


获得荣誉:

20229月    获评河南省优秀学士论文指导教师;

20236月    获评3499cc拉斯维加斯“优秀共产党员”称号;

202312月    获评3499cc拉斯维加斯“优秀实习指导教师”;

20246月    获评3499cc拉斯维加斯“优秀工会工作者”。




代表性论文:

[1] Gongming Zhu#, Guangjun Bao#, Yiping Li, Wangsheng Sun,* Jing Li, Liang Hong,* and Rui Wang*. Efficient Catalytic Kinetic Resolution of Spiro-epoxyoxindoles with Concomitant Asymmetric Friedel-Crafts Alkylation of Indoles. Angew. Chem. Int. Ed. 2017, 56, 5332 –5335.

[2] Wangsheng Sun#Gongming Zhu#, Chongyang Wu, Guofeng Li, Liang Hong,* and Rui Wang*. Organocatalytic Diastereo- and Enantioselective 1,3-Dipolar Cycloaddition of Azlactones and Methyleneindolinones. Angew. Chem. Int. Ed.2013, 52, 8633–8637.

[3] Gongming Zhu#, Yiping Li#, Guangjun Bao, Wangsheng Sun,* Liwu Huang, Liang Hong,* and Rui Wang*. Catalytic Kinetic Resolution of Spiro-Epoxyoxindoleswith 1 Naphthols: Switchable Asymmetric Tandem Dearomatization/Oxa-Michael Reaction and Friedel−Crafts Alkylation of 1 Naphthols at the C4 Position.ACS Catal.2018, 8, 1810−1816.

[4]Mengqi Wang, Shuping Yang, Xinge Li, Yingying Zheng, Yan Bai, Wenhan Luo, Gongming Zhu*, Junbiao Chang*, Bo Zhu*. Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2, Journal of Medicinal Chemistry, 2025, 68, 4101-4132.

[5]Gongming Zhu,* Haiyang Zhang, Liyang Han, Honglei Wang, Anlian Zhu, Lingjun Li*. Solvent-Driven Room-Temperature Curtius Rearrangements to Access Nucleotides Bearing Substituted Fused Pyridones, Organic Letters, 2024, 26(20): 4356-4360.

[6] Gongming Zhu, Guangjun Bao, Yiping Li, Junxian Yang, Wangsheng Sun, Jing Li, Liang Hong,* and Rui Wang*. Chiral Phosphoric Acid Catalyzed Asymmetric Oxidative Dearomatization of Naphthols with Quinones. Org. Lett., 2016, 18, 5288-5291.

[7] Gongming Zhu, Junxian Yang, Guangjun Bao, Ming Zhang, Jing Li, Yiping Li, Wangsheng Sun,* Liang Hong,* and Rui Wang*. Catalyst-controlled switch of regioselectivity in the asymmetric allylic alkylation of oxazolones with MBHCsChem. Commun. 2016, 52, 7882-7885.

[8] Gongming Zhu, Wangsheng Sun, Chongyang Wu, Guofeng Li, Liang Hong,* and Rui Wang*. Base-Catalyzed Diastereoselective [3 + 3] Annulation of 3-Isothiocyanatooxindoles and Azomethine Imines. Org. Lett. 2013, 15, 4988.

[9Jiaojiao Shen, Gongming Zhu, Yanbo You, Bianbian Huo, Fangyin Dai, Honglei Wang, Anlian Zhu and Lingjun Li. Designing a Light-Induced Glycosylation Reaction for Poststage Synthesis of ADP-2″-Deoxyribosyl Derivatives. Org. Lett. 2023, 21, 3961-3966.

[10]Mengqi Wang, Luyao Li, Shuping Yang, Fangyuan Guo, Gongming Zhu*, Bo Zhu*, Junbiao Chang*. Synthesis of novel oxazol-5-one derivatives containing chiral trifluoromethyl and isoxazole moieties as potent antitumor agents and the mechanism investigation. Bioorganic Chemistry. 2023, 135, 106505.